Main Office, PCL
Address: Haimen Biotech and Pharmaceutical Park, Riverside New District, Haimen, Jiangsu Province, China
Tel：+86 0513 68015200
Email:infor@pharmacorelab.com
Website: www.pharmacorelab.com
Branch Office, PCL
Address: Block 6D, 780 Cailun Road, China (Shanghai) pilot free trade zone. infor@pharmacorelab.com
Reaction BiologyReaction Biology is world leader in kinase and epigenetic drug discovery research–excellence due to gold standard assay formats with high reproducibility and low false positive/negative counts
|
Over 1,000 validated assays are available for high throughput screening based on |
Our experienced assay development team will realize all steps necessary for your customized screening project including |
|
• Enzymatic activity
• Protein-protein interaction
• Biophysical binding
• Membrane binding • Cell-based receptor functions |
• Construct selection
• Molecular cloning
• Protein production and purification
• Substrate identification
• Assay development and optimization • Primary, secondary and counter screenings |
Hit Evaluation via Secondary and Orthogonal Screening
• Validate primary hits by IC50 value determination
• Identify false positives/negatives by use of a second assay format
• Get more knowledge about the compound-target interaction such as kinetic data
• Use cell-based activity assays to validate the activity of your compound in a cellular environment and ensure it can cross the membrane to enter the cells
