Brain slice electrophysiology recording

The mammalian brain is the control center of all organs in the body. The normal function of the brain is determined by the electrochemical signal generation, transmission, receptions between neurons, while the critical determinant regulating the output of all neurons is the electrophysiological behavior that leads to the generation of action potentials. For all neurons, the generation of action potentials reflects the integration of intrinsic membrane properties and extrinsic inputs from neurotransmitters and modulators. The brain slice preparation has provided a powerful tool for examining the impact of these factors on the electrophysiological behavior of neurons in normal and pathological states. These in vitro preparations offer a direct approach to investigate the changes in electrical characteristics that govern neuronal behavior. Pharmacore Labs provide rat or mouse brain slice electrophysiological recordings for research and drugs on nervous system.